R-Squared Regimen

**Semantic type:** Therapeutic or Preventive Procedure

**Definition:** A regimen consisting of lenalidomide and rituximab that can be used in the treatment of primary central nervous system (CNS) lymphoma, Castleman disease, and non-Hodgkin lymphoma, including chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL), diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, mantle cell lymphoma, gastric and nongastric mucosa-associated lymphoid tissue (MALT) lymphoma, and nodal and splenic marginal zone lymphoma.

**Synonyms:** - Lenalidomide and Rituximab (R2) - Lenalidomide and Rituximab-abbs (R2) - Lenalidomide and Rituximab-arrx (R2) - Lenalidomide and Rituximab-blit (R2) - Lenalidomide and Rituximab-pvvr (R2) - Lenalidomide and Rituximab-rite (R2) - Lenalidomide and Rituximab-rixa (R2) - Lenalidomide and Rituximab-rixi (R2) - Lenalidomide-Rituximab - Lenalidomide/Rituximab - Lenalidomide/Rituximab Regimen - R-squared - R2 Regimen - Revlimid/Rituxan - Rituximab/Lenalidomide