Vesnarinone

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A cardiotonic quinolinone derivative, that suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an inhibitor of cyclin dependent kinase activity in p53-mediated cell cycle arrest. (NCI)

**Synonyms:** - 1-(3,4-Dimethoxybenzoyl)-4-(1,2,3,4-tetrahydro-2-oxo-6-quinolinyl)piperazine - 3,4-Dihydro-6-(4-(3,4-dimethoxybenzoyl)-1-pip- erazinyl)- 2(1H)-quinolinone - Arkin - Arkin-Z - DRG-0210 - Pieranometazine - Piperazine, 1-(3,4-dimethoxybenzoyl)-4-(1,2,3,4-tetrahydr- o -2-oxo-6-quinolinyl) - VESNARINONE