Goserelin Acetate

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** The acetate salt of a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH). Continuous, prolonged administration of goserelin in males results in inhibition of pituitary gonadotropin secretion, leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04)

**Synonyms:** - D-Ser(bu(t))(6)azgly(10)-LHRH Acetate - GOSERELIN ACETATE - ZDX - Zoladex - Zoladex