Activating PIK3R2 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the PIK3R2 gene that results in constitutive activation of phosphatidylinositol 3-kinase regulatory subunit beta and its downstream signaling pathways.

**Synonyms:** - Activating P85B Gene Mutation - Activating Phosphoinositide-3-Kinase Regulatory Subunit 2 Gene Mutation - Activating p85-BETA Gene Mutation - PIK3R2 Activating Mutation