PABPC1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PABPC1 wild-type allele is located in the vicinity of 8q22.3 and is approximately 37 kb in length. This allele, which encodes polyadenylate-binding protein 1, plays a role in mRNA binding. Mutations in the gene may be associated with head and neck squamous cell carcinoma and biliary tract carcinoma.

**Synonyms:** - PAB1 - PABP - PABP1 - PABPC2 - PABPL1 - Poly(A) Binding Protein Cytoplasmic 1 wt Allele - Poly(A) Binding Protein, Cytoplasmic 2 Gene - Poly(A)-Binding Protein, Cytoplasmic 2 Gene - Polyadenylate-Binding Protein, Cytoplasmic, 1 Gene