Imiquimod

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A synthetic agent with immune response modifying activity. As an immune response modifier (IRM), imiquimod stimulates cytokine production, especially interferon production, and exhibits antitumor activity, particularly against cutaneous cancers. Imiquimod's proapoptotic activity appears to be related to Bcl-2 overexpression in susceptible tumor cells. (NCI04)

**Synonyms:** - 1H-Imidazo(4,5-c)quinolin-4-amine, 1-(2-methylpropyl)- - 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline - Aldara - Aldara - IMIQUIMOD - R 837 - S 26308 - Zyclara - imiquimod