Efaproxiral

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity. Increasing tumor oxygenation reduces tumor radioresistance. (NCI04)

**Synonyms:** - 2-(4-(((3,5-Dimethylanilino)Carbonyl)Methyl)Phenoxy)-2-Methylpropionic Acid - 2-Dacmpp - EFAPROXIRAL - Efaproxyn - RSR-13 - RSR13 - RSR13 - efaproxiral