WN, Rat Strain

**Semantic type:** Mammal

**Definition:** Anterior pituitary tumors nearly 100% in females over 18 months of age, pheochromocytomas or preneoplastic nodules in adrenal medulla about 40% in males, granulocytic leukemia 14% in animals over 18 months of age. Rarely show hyperplastic cortical nodules or adrenal cortical adenomas. High incidence of severe chronic nephritis. (Snell 1967). High 10-week body weight in males (19/23), and high relative heart weight in 10-week old males (19/23) (Tanase et al 1982).

**Synonyms:** - WN