WF, Rat Strain

**Semantic type:** Mammal

**Definition:** A Wistar substrain derived by Furth (1945), this inbred rat strain is a white albino with pink eyes, genotype c. The Wistar Furth rat carries a heteropyenotic Y chromosome that is used as a cellular marker. Leukemia develops in 15-22% of these rats, which is characterized by mononuclear cells with reddish granules. The Wistar Furth rat exhibits good reproductive performance and is docile, with an averages life span of 22 months.

**Synonyms:** - WF - WISTAR FURTH - Wistar Furth Rat