Grade 3 Fibrosis Deep Connective Tissue, CTCAE

**Semantic type:** Finding

**Definition:** Severe induration; unable to slide or pinch skin; limiting joint or orifice movement (e.g., mouth, anus); limiting self-care ADL or severe impact on age-appropriate normal daily activity (pediatric)

**Synonyms:** - Grade 3 Fibrosis deep connective tissue - Grade 3 Fibrosis deep connective tissue