Grade 3 Leukoencephalopathy, CTCAE

**Semantic type:** Finding

**Definition:** Severe symptoms; extensive T2/FLAIR hyperintensities, involving periventricular white matter involving 2/3 or more of susceptible areas of cerebrum +/- moderate to severe increase in SAS and/or moderate to severe ventriculomegaly

**Synonyms:** - Grade 3 Leukoencephalopathy - Grade 3 Leukoencephalopathy