Dexniguldipine

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** Dexniguldipine is the (+)-enantiomer of the dihydropyridine derivate niguldipine. Dexniguldipine showed a binding affinity to the P-glycoprotein and therefore it is to be assumed to block the P-glycoprotein pumping mechanism and to modulate multidrug resistance. (NCI)

**Synonyms:** - (+)-(R)-3-(4,4-Diphenylpiperidino)Propyl Methyl 1,4-Dihydro-2,6-Dimethyl-4-(M-Nitrophenyl)-3,5-Pyridinedicarboxylate - B 859-35 Base Form - B8509-035 Base Form - B859 35 Base Form - DEXNIGULDIPINE - DNIG