Serum Sickness, CTCAE

**Semantic type:** Finding

**Definition:** A disorder characterized by a delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty-one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest marked discomfort and dyspnea.

**Synonyms:** - Serum Sickness - Serum Sickness, CTCAE 5.0 - Serum sickness - Serum sickness