454 Sequencing

**Semantic type:** Molecular Biology Research Technique

**Definition:** A proprietary next-generation DNA sequencing system from 454 Life Sciences that used large-scale parallel pyrosequencing. The system relied on fixing nebulized and adapter-ligated DNA fragments to small DNA-capture beads in a water-in-oil emulsion.

**Synonyms:** - 454 Sequencing Technology - LS 454 Sequencing - LS454 - LS454