Complete Genomics Sequencing

**Semantic type:** Molecular Biology Research Technique

**Definition:** A next-generation DNA sequencing service offered by Complete Genomics. Unamplified human genomic DNA is sheared into 500bp fragments and then amplified to create DNA nano-balls (DNBs). The DNBs are arrayed on a substrate and their sequence is determined by Combinatorial Probe-Anchor Ligation (cPAL) sequencing.

**Synonyms:** - Complete Genomics