C147535Level 3
Interleukin-23
**Semantic type:** Amino Acid, Peptide, or Protein
**Definition:** A heterodimeric cytokine composed of interleukin-12 subunit beta and interleukin-23 subunit alpha. This complex binds to the interleukin-23 receptor complex, which activates the JAK-STAT signaling pathway and modulates the proliferation, differentiation and effector functions of T-lymphocytes, natural killer cells and some myeloid lineage cells.
**Synonyms:** - IL-23 - IL23 - Interleukin 23
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