Interleukin-23 Receptor Complex

**Semantic type:** Amino Acid, Peptide, or Protein|Receptor

**Definition:** A heterodimeric complex composed of interleukin-12 receptor subunit beta-1 and interleukin-23 receptor. This receptor complex binds to interleukin-23, which activates the JAK-STAT signaling pathway and modulates the activation of T-lymphocytes, natural killer cells and some myeloid lineage cells.

**Synonyms:** - IL-23 Receptor - IL-23R - IL23R - IL23R/IL12RB1 Complex - Interleukin 23 Receptor - Interleukin-23 Receptor