Milodistim

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A recombinant fusion protein derived from the coding sequences of two growth factors, interleukin-3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF). Milodistim exhibits greater receptor binding affinity and colony stimulating activity than its parent cytokines. This agent stimulates proliferation of immature hematopoietic cells and allows the stimulation and expansion of multi-lineage hematopoiesis from immature bone marrow progenitor cells. (NCI04)

**Synonyms:** - 23-L-Leucine-27-L-aspartic acid-39-L-glutamic acid-colony-stimulating factor 2 (Human Clone pHG25 Protein Moiety Reduced), (127-9')-protein with 9-Glycine-10-glycine-11-glycine-12-glycine-13-L-serine-14-glycine-15-glycine-16-glycine-18-glycine-19-L-serine-34-L-aspartic acid-89-L-aspartic acid-9-152-interleukin 3 (human clone D11 Precursor Protein Moiety Reduced) - GM-CSF/IL-3 Fusion Protein - GM-CSF/IL3 Fusion Protein - Granulocyte-Macrophage Colony Stimulating Factor/Interleukin-3 Fusion Protein - MILODISTIM - PIXY321 - Pixykine