PTPRO wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PTPRO wild-type allele is located in the vicinity of 12p12.3 and is approximately 276 kb in length. This allele, which encodes receptor-type tyrosine-protein phosphatase O protein, plays a role in both glomerulus development and protein tyrosine phosphatase activity. Mutation of the gene may be associated with nephrotic syndrome.

**Synonyms:** - GLEPP1 - NPHS6 - PTP Phi - PTP-OC - PTP-U2 - PTPROT - PTPU2 - Protein Tyrosine Phosphatase, Receptor Type O wt Allele - Protein Tyrosine Phosphatase, Receptor Type, O Gene - R-PTP-O