IKBKE wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human IKBKE wild-type allele is located in the vicinity of 1q32.1 and is approximately 27 kb in length. This allele, which encodes inhibitor of nuclear factor kappa-B kinase subunit epsilon, is involved in the modulation of both interferon expression and the nuclear factor kappa-B signaling pathway. Amplification and overexpression of the gene is associated with breast carcinoma.

**Synonyms:** - IKK-E - IKK-I - IKKE - IKKI - Inhibitor of Kappa Light Polypeptide Gene Enhancer in B Cells, Kinase of, Epsilon Gene - Inhibitor of Kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase Epsilon Gene - Inhibitor of Nuclear Factor Kappa B Kinase Subunit Epsilon wt Allele - KIAA0151