Ruthenium-based Photosensitizer TLD1411

**Semantic type:** Pharmacologic Substance

**Definition:** A ruthenium-based photosensitizer (PS), that can potentially be used for photodynamic therapy (PDT). Upon intratumoral administration, the ruthenium-based PS TLD1411 targets mitochondria in tumor cells. Upon PDT, TLD1411 produces singlet molecular oxygen (O2), and induces a reactive oxygen species (ROS)-mediated tumor cell apoptosis.

**Synonyms:** - PS TLD1411 - TLD 1411 - TLD-1411 - TLD1411