Spastic Paraplegia 11

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal recessive condition caused by mutation(s) in the SPG11 gene, encoding spatacsin. It is a complicated sub-type of hereditary spastic paraplegia that has varying neurologic manifestations in addition to spasticity.

**Synonyms:** - HSP-TCC - Spastic Paraplegia, Autosomal Recessive, Complicated, with Thin Corpus Callosum