KDM4C wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KDM4C wild-type allele is located in the vicinity of 9p24.1 and is approximately 455 kb in length. This allele, which encodes lysine-specific demethylase 4C protein, plays a role in the demethylation of histone H3. Chromosomal aberrations involving the gene and aberrant expression of this gene may be associated with esophageal squamous cell carcinoma and other neoplastic diseases.

**Synonyms:** - GASC1 - Gene Amplified in Squamous Cell Carcinoma 1 - JHDM3C - JMJD2C - Jumonji Domain Containing 2C Gene - KIAA0780 - Lysine (K)-Specific Demethylase 4C Gene - Lysine Demethylase 4C wt Allele - TDRD14C - Tudor Domain Containing 14C Gene