MDS Neoantigen-specific Autologous T-lymphocytes

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of autologous T-lymphocytes that are exposed, ex vivo, to multiple, patient-specific myelodysplastic syndrome (MDS) stem cell neoantigens, with potential immunostimulating and antineoplastic activities. Upon infusion of the MDS neoantigen-specific autologous T-lymphocytes, the immunized T-cells specifically target and lyse cells expressing the MDS neoantigens.

**Synonyms:** - Autologous T-lymphocytes Targeting Patient-specific MDS Stem Cell Neoantigens - MDS Neoantigen-specific Autologous T-cells - MDS Neoantigen-specific Immunized Autologous T-cells - MDS-specific PACTN Agent - Personalized Adoptive Cellular Therapy Targeting MDS Stem Cell Neoantigens Agent - Personalized MDS Neoantigen-specific Autologous T-lymphocytes