Satraplatin

**Semantic type:** Inorganic Chemical|Pharmacologic Substance

**Definition:** An orally administered third generation platinum compound with potential antineoplastic activity. Satraplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in cell growth inhibition and apoptosis.

**Synonyms:** - (OC-6-43)-bis(acetato)amminedichloro(cyclohexylamine)platinum - (OC-6-43)-bis(acetato-O)amminedichloro(cyclohexanamine)platinum - BMS-182751 - BMY-45594 - JM 216 - JM-216 - Orplatna - SATRAPLATIN - platinum,bis(acetato-O)amminedichloro(cyclohexanamine)-,(OC-6-43) - satraplatin