Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Mitogen-activated protein kinase kinase kinase kinase 1 (833 aa, ~91 kDa) is encoded by the human MAP4K1 gene. This protein plays a role in the modulation of serine/threonine kinase-dependent signaling pathways.

**Synonyms:** - EC 2.7.11.1 - Hematopoietic Progenitor Kinase - Hematopoietic Progenitor Kinase 1 - MAP4K1 - MAPK/ERK Kinase Kinase Kinase 1 - MEK Kinase Kinase 1 - MEKKK 1