Phenyl Acetate

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** An aromatic fatty acid metabolite of phenylalanine with potential antineoplastic activity. Naturally occurring in mammals, phenylacetate induces differentiation, growth inhibition, and apoptosis in tumor cells. Implicated mechanisms of action include decreased protein prenylation, activation of the peroxisome proliferation-activated receptors, inhibition of DNA methylation, and depletion of glutamine. (NCI04)

**Synonyms:** - Acetic Acid Phenyl Ester - Acetylphenol - Acetylphenol - PHENYL ACETATE - Phenyl acetate - phenylacetate