SP140 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SP140 wild-type allele is located in the vicinity of 2q37.1 and is approximately 114 kb in length. This allele, which encodes nuclear body protein SP140, may be involved in the promotion of gene expression in leukocytes. Variation of this gene is associated with multiple sclerosis, Crohn disease, and chronic lymphocytic leukemia.

**Synonyms:** - LYSP100 - LYSP100-A - LYSP100-B - SP140 Nuclear Body Protein wt Allele - Speckled, 140-kD Gene