CLDN18 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CLDN18 wild-type allele is located in the vicinity of 3q22.3 and is approximately 35 kb in length. This allele, which encodes claudin-18 protein, is involved in tight junction assembly. Aberrant expression may be associated with gastric, pancreatic, esophageal, ovarian and lung neoplasms.

**Synonyms:** - Claudin 18 wt Allele - SFTA5 - SFTPJ - Surfactant Associated 5 Gene - Surfactant, Pulmonary Associated Protein J Gene - UNQ778/PRO1572