Cord Blood-derived Expanded Allogeneic Natural Killer Cells

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of human umbilical cord blood (UCB)-derived and ex vivo-expanded allogeneic natural killer (NK) cells, with immunomodulating and cytotoxic activities. Upon infusion of the cord blood-derived expanded allogeneic NK cells, these cells recognize and bind to tumor cells, and secrete perforins, granzymes, and cytokines, which cause cancer cell lysis.

**Synonyms:** - Allogeneic CB-derived Ex vivo-expanded NK Cells - CB-derived Expanded Allogeneic NK Cells - UCB-derived Expanded Allogeneic NK Cells - Umbilical Cord Blood-derived Expanded Allogeneic Natural Killer Cells