PALB2 Biallelic Inactivation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** The presence of mutations in both alleles of the PALB2 gene that either lead to loss of expression of the PALB2 protein or result in the translation of an inactive PALB2 protein.

**Synonyms:** - FANCN Biallelic Gene Inactivation - Fanconi Anemia, Complementation Group N Biallelic Gene Inactivation - PALB2 Biallelic Gene Inactivation - PNCA3 Biallelic Gene Inactivation - Partner and Localizer of BRCA2 Biallelic Gene Inactivation