GREM1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GREM1 wild-type allele is located in the vicinity of 15q13.3 and is approximately 27 kb in length. This allele, which encodes gremlin-1 protein, plays a role in antagonizing bone morphogenetic protein signaling pathways. Mutation of the gene is associated with hereditary mixed polyposis syndrome 1.

**Synonyms:** - C15DUPq - CKTSF1B1 - CRAC1 - CRCS4 - Cell Proliferation-Inducing Gene 2 - Colorectal Adenoma and Carcinoma 1 Gene - Cystine Knot Superfamily 1, BMP Antagonist 1 Gene - DAND2 - DRM - DUP15q - GREMLIN - Gremlin 1 Homolog, Cysteine Knot Superfamily Gene - Gremlin 1, Cysteine Knot Superfamily, Homolog (Xenopus laevis) Gene - Gremlin 1, Cysteine Knot Superfamily, Homolog Gene - Gremlin 1, DAN Family BMP Antagonist wt Allele - HMPS - HMPS1 - IHG-2 - MPSH - PIG2