6-Ketoprostaglandin F1alpha

**Semantic type:** Organic Chemical

**Definition:** A form of prostaglandin F1alpha that has been modified with a keto group at position 6. 6-Ketoprostaglandin F1alpha (6-ketoPGF1a) is an inactive metabolite derived from prostaglandin I2 (PGI2). The concentration of 6-ketoPGF1a in a sample may be correlated with the levels of PGI2 synthesis. 6-KetoPGF1a levels are elevated in certain types of cancers.

**Synonyms:** - (13E,15S)-9alpha,11alpha,15-trihydroxy-6-oxoprost-13-en-1-oic acid - 6-Keto-PGF1alpha - 6-Keto-Prostaglandin F1-Alpha - 6-Keto-Prostaglandin F1a - 6-Keto-Prostaglandin F1alpha - 6-KetoPGF1a - 6-Ketoprostaglandin F1-Alpha - 6-Oxo-PGF1a - 6-Oxo-PGF1alpha - 6-Oxoprostaglandin F1a - 6-Oxoprostaglandin F1alpha - Prost-13-en-1-oic acid, 9,11,15-trihydroxy-6-oxo-, (9alpha,11alpha,13E,15S)-