Sodium Zirconium Cyclosilicate

**Semantic type:** Pharmacologic Substance

**Definition:** An insoluble, non-absorbed inorganic material used as a potassium binder and a treatment for hyperkalemia. Upon administration as an oral suspension, sodium zirconium cyclosilicate selectively targets and binds to potassium in the gastrointestinal (GI) tract, exchanging its sodium ions for potassium ions. This increases fecal potassium excretion, decreases the concentration of free potassium in the GI lumen, and lowers serum potassium levels.

**Synonyms:** - Lokelma - Lokelma - SODIUM ZIRCONIUM CYCLOSILICATE