Activating FGFR Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of an FGFR family gene that results in constitutive activation the encoded fibroblast growth factor receptor protein and its downstream signaling pathways.

**Synonyms:** - Activating FGF Receptor Gene Family Mutation - Activating FGF Receptor Gene Mutation - Activating FGFR Family Gene Mutation - Activating FGFR Family Mutation - Activating FGFR Mutation - Activating Fibroblast Growth Factor Receptor Family Gene Mutation - Activating Fibroblast Growth Factor Receptor Gene Mutation - Gain-of-Function FGFR Gene Mutation