DNMT3 Family

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** A family of proteins involved in methylation of DNA. There are three proteins in this family. DNA (cytosine-5)-methyltransferase (DNMT) 3A and DNMT3B are DNA methyltransferases that catalyze the methylation of hemimethylated and unmethylated CpG at the same rate. DNMT3-like (DNMT3L) has no enzymatic activity; instead this protein interacts with other members of the family and regulates their enzymatic activity.

**Synonyms:** - DNA (Cytosine-5)-Methyltransferase 3 - DNA (Cytosine-5)-Methyltransferase 3 Family - DNMT3