CRIPTO wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CRIPTO wild-type allele is located in the vicinity of 3p21.31 and is approximately 8 kb in length. This allele, which encodes protein Cripto, is involved in regulation of signaling by Nodal homolog. Mutation of the gene is associated with defects in forebrain development.

**Synonyms:** - CR - CR-1 - CRGF - Cripto, EGF-CFC Family Member wt Allele - Cripto-1 - TDGF1 - TDGF1 wt Allele - Teratocarcinoma-Derived Growth Factor 1 Gene