Autologous Tumor Infiltrating Lymphocytes MDA-TIL

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of autologous tumor infiltrating lymphocytes (TILs) with potential antineoplastic activity. TILs are isolated from a patient's tumor tissue, then cultured and expanded in vitro in the presence of interleukin-2 (IL-2) and an agonistic anti-4-1BB (CD137) antibody. Upon infusion of the autologous expanded TILs back into the patient, the cells specifically recognize, target, and kill the patient's tumor cells.

**Synonyms:** - MDA Autologous TILs - MDA Autologous Tumor Infiltrating Lymphocytes - MDA-TILs