Guretolimod

**Semantic type:** Pharmacologic Substance

**Definition:** A synthetic, small molecule, toll-like receptor (TLR) 7 agonist, with potential immunostimulatory and antineoplastic activities. Upon intravenous administration, guretolimod activates TLR7, resulting in type I interferon secretion and activation of cytotoxic T-lymphocyte (CTL)-mediated anti-tumor immune responses. TLR7 is a member of the TLR family, which plays a fundamental role in pathogen recognition and activation of innate immunity.

**Synonyms:** - (((4-((2-Amino-4-(((3s)-1-hydroxyhexan-3-yl)amino)-6-methylpyrimidin-5-yl)methyl)-3- methoxyphenyl)methyl)(2,2,2-trifluoroethyl)amino)acetic Acid - DSP 0509 - DSP-0509 - DSP0509 - GURETOLIMOD - TLR7 Agonist DSP-0509 - Toll-like Receptor 7 Agonist DSP-0509