Furosemide Topical Gel CLS006

**Semantic type:** Pharmacologic Substance

**Definition:** A sulfamoylanthranilic acid derivative and loop diuretic, with potential antiviral activity. Upon topical administration, furosemide gel inhibits potassium influx by interacting with cell membrane ion co-transporter, Na+-K+-2Cl-co-transporter-1(NKCC1; SLC12A2). This may inhibit potassium influx and prevent the replication of DNA viruses, such as human papillomavirus (HPV), that rely on potassium for replication.

**Synonyms:** - CLS 006 - CLS-006 - CLS006 - Furosemide Topical Gel CLS 006 - Furosemide Topical Gel CLS-006