Adoptive Immunotherapy

**Semantic type:** Therapeutic or Preventive Procedure

**Definition:** A technique for enhancing cell-mediated immunity by: 1) artificially increasing the number of specific immunocompetent cells through inoculation of either ex-vivo expanded primarily activated cytotoxic lymphocytes or genetically engineered lymphocytes with enhanced cytotoxic ability or 2) by altering tumor cells to make them more immunogenic.

**Synonyms:** - ACT - ACT Therapy - Adoptive Cell Immunotherapy - Adoptive Cell Transfer - Adoptive Cell Transfer Immunotherapy - Adoptive Cell Transfer Therapy - adoptive cellular immunotherapy - adoptive cellular therapy - cellular adoptive immunotherapy