Esterified Estrogens

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A mixture of the sodium salts of the sulfate esters of estrogen including sodium estrone sulfate, sodium equilin sulfate and the concomitant component, 17 alpha-estradiol, that is used for estrogen replacement. Estrogens bind to nuclear receptors in estrogen-responsive tissues and modulate the secretion of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), stimulate skeletal growth, and have a widespread effect on metabolic processes including protein transport and electrolyte balance.

**Synonyms:** - ESTROGENS, ESTERIFIED - Estrogens, Esterified - Menest (BR)