Grade 3 Retinopathy of Prematurity, AE

**Semantic type:** Finding

**Definition:** An adverse event in a newborn characterized by type 1 prethreshold retinopathy of prematurity (ROP) (zone 1 any stage with plus disease; zone 1 International Classification of Retinopathy of Prematurity (ICROP) stage 3 without plus disease; zone 2 ICROP stage 2 or 3 with plus disease); threshold ROP; requiring major care changes (e.g. laser intervention, intravitreal anti-VEGF therapy or operative management).

**Synonyms:** - Grade 3 Retinopathy of Prematurity - Grade 3 Retinopathy of Prematurity, Adverse Event - Grade 3 RoP, AE