Grade 4 Persistent Pulmonary Hypertension of the Newborn, AE

**Semantic type:** Finding

**Definition:** A persistent pulmonary hypertension adverse event in a newborn characterized by life-threatening respiratory and/or hemodynamic compromise; extracorporeal membrane oxygenation (ECMO) required; oxygenation index greater than 40.

**Synonyms:** - Grade 4 PPHN, AE - Grade 4 Persistent Pulmonary Hypertension of the Newborn - Grade 4 Persistent Pulmonary Hypertension of the Newborn, Adverse Event