Autologous HPV-specific Cytotoxic T Lymphocytes

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A population of autologous cytotoxic T-lymphocytes (CTLs) that are specifically reactive to human papillomavirus (HPV), with potential antiviral and antineoplastic activities activities. Upon infusion of the autologous HPV-specific CTLs, these CTLs induce selective toxicity in HPV-positive cancer cells and other HPV-infected cells. HPV is associated with various cancer cell types.

**Synonyms:** - Autologous HPV Specific Immune Lymphocytes - Autologous HPV-CTLs