Soluble Interleukin-6 Receptor Subunit Alpha

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Soluble interleukin-6 receptor subunit alpha is encoded by the human IL6R gene. This protein, which is produced by metalloproteinase-mediated cleavage of the membrane-bound form, is involved in the modulation of interleukin-6-mediated signaling by CD4-positive T-lymphocytes.

**Synonyms:** - Soluble CD126 - Soluble CD126 Antigen - Soluble IL-6 Receptor - Soluble IL-6 Receptor Alpha - Soluble IL-6R - Soluble IL-6R Subunit Alpha - Soluble IL-6R-Alpha - Soluble IL-6RA - Soluble IL6R - Soluble IL6RA - Soluble Interleukin 6 Receptor - Soluble Interleukin 6 Receptor Subunit Alpha - Soluble Interleukin-6 Receptor - Soluble gp80 - sIL-6R - sIL-6RA