Inactivating BRAF Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the BRAF gene that inhibits expression or results in the translation of either low-activity or inactive forms of the serine/threonine-protein kinase B-raf protein.

**Synonyms:** - BRAF Class 3 Gene Mutation - BRAF Class 3 Mutation - BRAF Class III Alteration - BRAF Class III Gene Mutation - BRAF Gene Inactivation - BRAF Inactivation - Class 3 BRAF Gene Mutation - Class 3 BRAF Mutation - Class III BRAF Gene Mutation - Inactivating B-RAF Gene Mutation - Inactivating B-RAF1 Gene Mutation - Inactivating BRAF Mutation - Inactivating BRAF1 Gene Mutation - Inactivating v-raf Murine Sarcoma Viral Oncogene Homolog B1 Gene Mutation