Histone H3 Lysine 79

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** The lysine residue found at amino acid position 79 in the histone H3 protein. Methylation of this residue by DOT1L protein disrupts telomeric silencing and may be a marker for cellular transformation and disease progression in patients with leukemia.

**Synonyms:** - H3K79 - Histone H3 Lys79 - Histone H3 Lys80 - Histone H3 Lysine 80 - Lysine 79 of Histone H3