Succinate Dehydrogenase-Deficient Renal Cell Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** A very rare renal cell carcinoma that usually affects young adults. It is characterized by mutations in one of the four subunits of the SDH complex (SDHA, SDHB, SDHC, or SDHD gene). Most frequently, the mutations occur in the SDHB subunit. It has a relatively good prognosis.

**Synonyms:** - SDH Deficient Renal Cell Carcinoma - SDH-Deficient Renal Cell Carcinoma - SDH-RCC - Succinate Dehydrogenase Renal Cell Carcinoma