Rhenium Re-188 Etidronate

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A synthetic compound containing the bisphosphonate etidronate (hydroxyethylidene diphosphonate, HEDP) labeled with rhenium Re188, a beta-emitting radioisotope with potential antineoplastic activity. Upon administration, Re-188 etidronate binds to hydroxyapatite in bone, delivering a cytotoxic dose of beta radiation to primary and metastatic bone tumors. The beta-radiation may provide localized anti-tumor radiotoxicity while sparing extramedullary bone marrow tissues.

**Synonyms:** - 188Re-HEDP - 88Re-Etidronate - RHENIUM RE-188 ETIDRONATE - Re 188 Etidronic Acid - Re 188 Hydroxyethylidene Diphosphonate - Re-188 Etidronate - Re-188 HEDP - Re-188 Hydroxyethylidene Diphosphonate - Re-188Etidronate - Rhenium Re-188 Hydroxyethylidene Diphosphonate (SY) - Rhenium-188 Etidronate - Rhenium-188 HEDP